Historians seem to have found that it’s origins date back to an Umbrian immigration. It became Etruscan land. With time the river Esino became the southern boarder of the Galli Senoni territory. 

And finally with the Roman legion “Aesis”  became a colony. First County and then Free Community the city began to grow and spread towards the nearby “Castelli” and feudal abbeys. 

The territorial expansion flourished with the protection of Federico II of Svevia who was born here in 1194. The Roman Aesis is situated around Federico II square  in the proximity of the Cardo and Decumano crossing.

The medieval centre is closed within a complete “Cage of Wall”. This medieval centre features many buildings, convents, churches and narrow pebble stone streets that when are too steep have adjacent staircase. In the 1700’s the centre finally expanded out of these walls along what is know as Corso Matteotti with many churches, nobel buildings, and new residential palaces. Corso Matteotti is crowned of with Arco Clementino.

Mills, rolling wool and fillet working, tanneries, sawmills and hydraulic lathes; then silk spinning, waste-silk factory, paper factory and other industries had been the first to need water and electricity. In this town all has been connected to agriculture. 

The population of the fields has been an enormous resource that industry turned to in order to have rural manpower at small cost, reliable and persistent, the one that would know how to endure hard working schedules and difficult working conditions. 

A worker from Jesi has always had excellent natural qualities. He is serious, laborious, inventive, practical, concrete. From mechanics, blacksmiths, wagon-makers, constructors and repairmen were born artisans and small undertakers who have, gradually, invented new tools, have changed working techniques, have transformed factories and have created small industries. 

From the primary manufactures of the 19th century to the industry - the passage is laborious but short. At the beginning of the 20th century, the town registers - a part from eleven silk spinning factories - twelve factories of silkworms plus another twenty-two factories in general, with personnel numbering one thousand and seven hundred units. The total index of industrialisation is very high, and helps the town to gain the name of "Little Milan of the Marches". 

Agricultural equipment and technical instruments represent bases for the appearance of important industries of agrarian mechanics. 

Today, considering the large number of industries in Jesi, it is important to remember the biggest complexes of food industry: sugar refinery, milk and cheese products; of wood carpentry: kitchens; of mechanics: apparatuses for industrial centrifuge, street building machines, oil and wine production machines.